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Dec 2001
The amount of scurfin protein determines peripheral T cell number and responsiveness.
J ImmunolKhattri R, Kasprowicz D, Cox T, Mortrud M, Appleby MW, Brunkow ME, Ziegler SF, Ramsdell F -
Dec 2001
Generation of high quantities of viral and tumor-specific human CD4+ and CD8+ T-cell clones using peptide pulsed mature dendritic cells.
J Immunol MethodsFonteneau JF, Larsson M, Somersan S, Sanders C, Münz C, Kwok WW, Bhardwaj N, Jotereau F -
Nov 2001
Rapid epitope identification from complex class-II-restricted T-cell antigens.
Trends ImmunolKwok WW, Gebe JA, Liu A, Agar S, Ptacek N, Hammer J, Koelle DM, Nepom GT -
Oct 2001
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation.
J Biol ChemSchubert LA, Jeffery E, Zhang Y, Ramsdell F, Ziegler SF -
Sep 2001
T cell selection and differential activation on structurally related HLA-DR4 ligands.
J ImmunolGebe JA, Novak EJ, Kwok WW, Farr AG, Nepom GT, Buckner JH -
Sep 2001
Islet cell antibodies and glutamic acid decarboxylase antibodies, but not the clinical phenotype, help to identify type 1(1/2) diabetes in patients presenting with type 2 diabetes.
MetabolismJuneja R, Hirsch IB, Naik RG, Brooks-Worrell BM, Greenbaum CJ, Palmer JP -
Jun 2001
Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset.
Int ImmunolNovak EJ, Masewicz SA, Liu AW, Lernmark A, Kwok WW, Nepom GT -
Jun 2001
Tetramer-guided epitope mapping: rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens.
J ImmunolNovak EJ, Liu AW, Gebe JA, Falk BA, Nepom GT, Koelle DM, Kwok WW -
May 2001
The role of the DR4 shared epitope in selection and commitment of autoreactive T cells in rheumatoid arthritis.
Rheum Dis Clin North AmNepom GT -
Apr 2001
Intermolecular antigen spreading occurs during the preclinical period of human type 1 diabetes.
J ImmunolBrooks-Worrell B, Gersuk VH, Greenbaum CJ, Palmer JP -
Mar 2001
CD8 CTL from genital herpes simplex lesions: recognition of viral tegument and immediate early proteins and lysis of infected cutaneous cells.
J ImmunolKoelle DM, Chen HB, Gavin MA, Wald A, Kwok WW, Corey L -
Feb 2001
Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).
Proc Natl Acad Sci U S ANepom GT, Lippolis JD, White FM, Masewicz S, Marto JA, Herman A, Luckey CJ, Falk B, Shabanowitz J, Hunt DF, Engelhard VH, Nepom BS -
Feb 2001
Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria.
DiabetesGreenbaum CJ, Cuthbertson D, Krischer JP, Disease Prevention Trial of Type I Diabetes Study Group. -
Jan 2001
Low-dose streptozotocin induces sustained hyperglycemia in Macaca nemestrina.
AutoimmunityGaur LK, Nepom GT, Lernmark A -
Jan 2001
Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65.
AutoimmunityMasewicz SA, Meldrum N, Gersuk V, Gaur L, Hagopian W, Moriarity L, Nepom GT