Benaroya Research Institute (BRI) is on a mission to predict, prevent, reverse and cure immune system diseases. We study the cells and processes within the immune system, how and why immune system diseases start, and how to rebalance the immune system back to health. Our focus spans a wide variety of immune system diseases – including autoimmune diseases, asthma, allergy, cancer and COVID-19 – with the goal of transforming our understanding of how to prevent and treat these conditions.
Collaboration defines our work. We build teams within our institute and with partners around the world to take on some of the most difficult questions in immunology. This approach moves us closer to our vision of a healthy immune system for everyone.
Our Centers of Discovery: A pipeline from lab research to life-changing care
Fundamental Immunology
Examining cells, genes and molecules to better understand the immune system
Translational Immunology
Exploring how lab discoveries could become potential new therapies; studying how therapies alter the immune system
Interventional Immunology
Using clinical trials to test and refine new and more effective therapies
Systems Immunology
Analyzing large and complex data sets across all Centers to identify patterns and accelerate breakthroughs
Our Biorepositories
Our Core Labs: Building and using the latest tools and technologies
Cell and Tissue Analysis
Analyzing, sorting, selecting and identifying cells with a variety of parameters. These tools are available to scientists within BRI and to those from other institutions.
Genomics
Providing resources to study the structure and function of the human genome. This includes sequence analysis, from sample processing through data generation, and basic bioinformatics analysis.
Human Immunophenotyping
Studying immune system diseases by helping identify underlying mechanisms of disease, developing biomarkers of disease and informing new treatments.
Tetramers
Providing MHC class II tetramer reagents, an innovative tool invented at BRI that helps scientists find and study very specific cells.
