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Nov 2023
Colonic mucosal associated invariant T cells in Crohn's disease have a diverse and non-public T cell receptor beta chain repertoire.
PLoS OneKonecny AJ, Shows DM, Lord JD -
Nov 2023
MDR1-expressing CD4+ T cells with Th1.17 features resist to neoadjuvant chemotherapy and are associated with breast cancer clinical response
J Immunother CancerDi Roio A, Hubert M, Besson L, Bossennec M, Rodriguez C, Grinberg-Bleyer Y, Lalle G, Moudombi L, Schneider R, Degletagne C, Treilleux I, Campbell DJ, Metzger S, Duhen T, Trédan O, Caux C, Ménétrier-Caux C -
Oct 2023
Th2 cell clonal expansion at diagnosis in human type 1 diabetes.
Clin ImmunolNarsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD -
Oct 2023
Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes.
Cell Rep MedSims EK, Kulkarni A, Hull A, Woerner SE, Cabrera S, Mastrandrea LD, Hammoud B, Sarkar S, Nakayasu ES, Mastracci TL, Perkins SM, Ouyang F, Webb-Robertson BJ, Enriquez JR, Tersey SA, Evans-Molina C, Long SA, Blanchfield L, Gerner EW, Mirmira RG, DiMeglio LA -
Oct 2023
Self-reactive germline-like TCR alpha chains shared between blood and pancreas.
Res SqLinsley P, Nakayama M, Balmas E, Chen J, Pour F, Bansal S, Serti E, Speake C, Pugliese A, Cerosaletti K -
Oct 2023
Janus kinase inhibitors differentially inhibit specific cytokine signals in the mesenteric lymph node cells of IBD patients.
J Crohns ColitisHindmarch DC, Malashanka S, Shows DM, Clarke AS, Lord JD -
Oct 2023
Antigen-level resolution of commensal-specific B cell responses enabled by phage-display screening and B cell tetramers.
bioRxivHarrison OJ, et al. -
Oct 2023
Trimodal single-cell profiling reveals a novel pediatric CD8αα(+) T cell subset and broad age-related molecular reprogramming across the T cell compartment.
Nat ImmunolThomson Z, He Z, Swanson E, Henderson K, Phalen C, Zaim SR, Pebworth MP, Okada LY, Heubeck AT, Roll CR, Hernandez V, Weiss M, Genge PC, Reading J, Giles JR, Manne S, Dougherty J, Jasen CJ, Greenplate AR, Becker LA, Graybuck LT, Vasaikar SV, Szeto GL, Savage AK, Speake C, Buckner JH, Li XJ, Bumol TF, Wherry EJ, Torgerson TR, Vella LA, Henrickson SE, Skene PJ, Gustafson CE -
Oct 2023
Vedolizumab Efficacy Is Associated With Decreased Intracolonic Dendritic Cells, Not Memory T Cells.
Inflamm Bowel DisBoden EK, Kongala R, Hindmarch DC, Shows DM, Juarez JG, Lord JD -
Oct 2023
Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: a systematic review.
Commun Med (Lond)Felton JL, Griffin KJ, Oram RA, Speake C, Long SA, Onengut-Gumuscu S, Rich SS, Monaco GSF, Evans-Molina C, DiMeglio LA, Ismail HM, Steck AK, Dabelea D, Johnson RK, Urazbayeva M, Gitelman S, Wentworth JM, Redondo MJ, Sims EK, ADA/EASD PMDI -
Oct 2023
Genotype-stratified treatment for monogenic insulin resistance: a systematic review.
Commun Med (Lond)Semple RK, Patel KA, Auh S, ADA/EASD PMDI, Brown RJ, Long SA, Speake C -
Oct 2023
Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review.
Commun Med (Lond)Bodhini D, Morton RW, Santhakumar V, Nakabuye M, Pomares-Millan H, Clemmensen C, Fitzpatrick SL, Guasch-Ferre M, Pankow JS, Ried-Larsen M, Franks PW, ADA/EASD PMDI, Tobias DK, Merino J, Mohan V, Loos RJF, Long SA, Speake C -
Oct 2023
Utility and precision evidence of technology in the treatment of type 1 diabetes: a systematic review.
Commun Med (Lond)Jacobsen LM, Sherr JL, Considine E, Chen A, Peeling SM, Hulsmans M, Charleer S, Urazbayeva M, Tosur M, Alamarie S, Redondo MJ, Hood KK, Gottlieb PA, Gillard P, Wong JJ, Hirsch IB, Pratley RE, Laffel LM, Mathieu C, ADA/EASD PMDI, Long SA, Speake C -
Oct 2023
Participant characteristics in the prevention of gestational diabetes as evidence for precision medicine: a systematic review and meta-analysis.
Commun Med (Lond)Lim S, Takele WW, Vesco KK, Redman LM, Hannah W, Bonham MP, Chen M, Chivers SC, Fawcett AJ, Grieger JA, Habibi N, Leung GKW, Liu K, Mekonnen EG, Pathirana M, Quinteros A, Taylor R, Ukke GG, Zhou SJ, ADA/EASD PMDI, Josefson J, Long SA, Speake C -
Oct 2023
The use of precision diagnostics for monogenic diabetes: a systematic review and expert opinion.
Commun Med (Lond)Murphy R, Colclough K, Pollin TI, Ikle JM, Svalastoga P, Maloney KA, Saint-Martin C, Molnes J, ADA/EASD PMDI, Misra S, Aukrust I, de Franco E, Flanagan SE, Njølstad PR, Billings LK, Owen KR, Gloyn AL, Long SA, Speake C
