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Nov 2014
Molecular signatures differentiate immune states in type 1 diabetic families.
DiabetesChen YG, Cabrera SM, Jia S, Kaldunski ML, Kramer J, Cheong S, Geoffrey R, Roethle MF, Woodliff JE, Greenbaum CJ, Wang X, Hessner MJ -
Oct 2014
A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4
Nat ImmunolAlsina L, Israelsson E, Altman MC, Dang KK, Ghandil P, Israel L, von Bernuth H, Baldwin N, Qin H, Jin Z, Banchereau R, Anguiano E, Ionan A, Abel L, Puel A, Picard C, Pascual V, Casanova JL, Chaussabel D -
Oct 2014
Copy number loss of the interferon gene cluster in melanomas is linked to reduced T cell infiltrate and poor patient prognosis.
PLoS OneLinsley PS, Speake C, Whalen E, Chaussabel D -
Oct 2014
Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.
Proc Natl Acad Sci U S AYang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW -
Oct 2014
Biogeography and individuality shape function in the human skin metagenome
NatureOh J, Byrd AL, Deming C, Conlan S, NISC Comparative Sequencing Program, Kong HH, Segre JA -
Oct 2014
The role of basophils and proallergic cytokines, TSLP and IL-33, in cutaneously sensitized food allergy.
Int ImmunolMuto T, Fukuoka A, Kabashima K, Ziegler SF, Nakanishi K, Matsushita K, Yoshimoto T -
Sep 2014
Circulating Type-1 Anti-Tumor CD4(+) T Cells are Preferentially Pro-Apoptotic in Cancer Patients.
Front OncolWesa AK, Mandic M, Taylor JL, Moschos S, Kirkwood JM, Kwok WW, Finke JH, Storkus WJ -
Sep 2014
IFNαR signaling in effector but not regulatory T cells is required for immune dysregulation during type I IFN-dependent inflammatory disease.
J ImmunolSrivastava S, Koch LK, Campbell DJ -
Sep 2014
PathoScope 2.0: a complete computational framework for strain identification in environmental or clinical sequencing samples
MicrobiomeHong C, Manimaran S, Shen Y, Perez-Rogers JF, Byrd AL, Castro-Nallar E, Crandall KA, Johnson WE -
Sep 2014
Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components.
J Allergy Clin ImmunolReeves SR, Kolstad T, Lien TY, Elliott M, Ziegler SF, Wight TN, Debley JS -
Sep 2014
Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.
DiabetesMcGinty JW, Chow IT, Greenbaum CJ, Odegard JM, Kwok WW, James EA -
Sep 2014
Immune regulation by intralymphatic immunotherapy with modular allergen translocation MAT vaccine.
AllergyZaleska A, Eiwegger T, Soyer O, van de Veen W, Rhyner C, Soyka MB, Bekpen C, Demiröz D, Treis A, Söllner S, Palomares O, Kwok WW, Rose H, Senti G, Kündig TM, Ozoren N, Jutel M, Akdis CA, Crameri R, Akdis M -
Aug 2014
IL-33 and thymic stromal lymphopoietin mediate immune pathology in response to chronic airborne allergen exposure.
J ImmunolIijima K, Kobayashi T, Hara K, Kephart GM, Ziegler SF, McKenzie AN, Kita H -
Aug 2014
DOCK8 regulates protective immunity by controlling the function and survival of RORγt+ ILCs.
Nat CommunSingh AK, Eken A, Fry M, Bettelli E, Oukka M -
Aug 2014
Clinical PathoScope: rapid alignment and filtration for accurate pathogen identification in clinical samples using unassembled sequencing data
BMC BioinformaticsByrd AL, Perez-Rogers JF, Manimaran S, Castro-Nallar E, Toma I, McCaffrey T, Siegel M, Benson G, Crandall KA, Johnson WE