Autoimmune Life Blog

When Nina and Georg Pedersen were writing charitable gifts into their will, they had two goals: finding meaningful ways to honor their family and recognizing the expert care they’ve received at Virginia Mason.

Understanding how viruses impact the immune system has long been a focus at BRI. Two years of pandemic life have made answering two questions particularly important: Can respiratory viruses like the common cold or COVID-19 start the chain reaction that leads to immune system disease?

One question inspired Erik Wambre, PhD, to dedicate his career to allergy research. “Why can most people eat peanuts without a problem, but some people have a serious reaction to just a small amount?” he says. “What makes one person allergic and not another?”

To most people, the gut is just a part of your body that helps digest food.

A pattern emerged at the beginning of the pandemic: COVID-19 led to an overly aggressive immune response in some people, causing deadly inflammation.

At age 14, Mara, who is now in her 30s, was diagnosed with type 1 diabetes. A few years ago, she also learned she had celiac disease and was recently confronted with a rheumatoid arthritis diagnosis.

A team led by Peter Linsley, PhD, and Karen Cerosaletti, PhD, recently uncovered a clue that could help solve the mystery of why and how T1D starts and maybe even open the door to new therapies that stop the disease.

Rain was pouring down on the morning of Gretchen Schoenstein’s 100th half marathon — a day she’d dreamt of but wasn’t sure would ever come. That morning, the event’s producer asked her to share a few words.

Becky Ronan has seen firsthand how research has impacted life for people with Down syndrome. When her older brother Kevin was born with Down syndrome in 1967, her parents were advised not to bring him home. “Most people with Down syndrome were put in institutions,” Becky says.

For nearly 20 years, Dr. Buckner has been working to find a more targeted approach with fewer side effects. And she’s among a handful of scientists pursuing an intriguing idea: Can we use gene editing to change cells that cause disease into cells that protect you from disease?