The Immune Tolerance Network's LEAP study manuscript was selected by the New England Journal of Medicine as one of the most notable articles of 2015. The LEAP study provided conclusive evidence that early consumption of peanut by high-risk infants prevents the development of peanut allergy later on. The Immune Tolerance Network is led by BRI.

In the introductory letter from NEJM Editor-in-Chief, Jeffrey Drazen, he notes that “this digital collection represents the cream of the crop, the dozen studies from 2015 that we think will have the biggest influence on medicine.”